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JWH-018 can be a sort of analgesic chemical through the naphthoylindole household that features as a full agonist at the two the CB1 and CB2 cannabinoid receptors. It had been 1st synthesized by Dr. John W. Huffman and is found out in herbal smoking blends like Spice. The analgesic effects of cannabinoid ligands, which can be mediated by CB1 recept